Titanium Dioxide (13463-67-7)
Titanium Dioxide is a particulate / dust with CAS Registry Number 13463-67-7. Under the OSHA air contaminants standard (29 CFR 1910.1000), its Permissible Exposure Limit (PEL) — the legal 8-hour time-weighted average (TWA) for general industry — is 15 mg/m3. The principal target organs are the Lungs, and workplace air is sampled and analyzed by NIOSH 0600.
Exposure Limits at a Glance
| Limit | Value | Basis |
|---|---|---|
| OSHA PEL (8-hr TWA) | 15 mg/m3 | 29 CFR 1910.1000 |
| NIOSH REL | See note below | NIOSH Pocket Guide |
| Hazard Class | Particulate / Dust | Particulate |
| Target Organs | Lungs | NIOSH / OSHA |
| Sampling Method | NIOSH 0600 | NIOSH Manual of Analytical Methods |
NIOSH REL note: NIOSH RELs are often 10x lower than the PEL and include a respirable fraction. The REL is a non-regulatory recommendation; where a NIOSH REL exists it is typically more protective than the OSHA PEL.
How It Enters the Body & Health Effects
Exposure to Titanium Dioxide is assessed against the Lungs — the organ systems most consistently affected in occupational studies. Employers must ensure no employee’s 8-hour TWA exceeds the 15 mg/m3 PEL, and must use engineering controls, work practices, and — where required — respiratory protection to keep exposures at or below that level.
- Hazard class: Particulate / Dust. Particulate-class agents are managed with the hierarchy of controls (elimination, substitution, engineering controls, administrative controls, then PPE).
- Monitoring: collect personal air samples in the breathing zone and submit them under NIOSH 0600 for laboratory analysis.
- Medical surveillance: consult the OSHA substance-specific standards and the NIOSH Pocket Guide when the target organs are the Lungs.
Sampling & Compliance Notes
- Determine whether the exposure is a full-period 8-hour TWA or a short-term / ceiling scenario. Ceiling and STEL excursions apply to several Particulate-class agents regardless of the 8-hour average.
- Calibrate personal sampling pumps before and after each shift and record flow rates; method NIOSH 0600 specifies media, flow, and analysis.
- Compare analytical results to the OSHA PEL of 15 mg/m3 and the NIOSH REL. Document the higher of the two for internal exposure-control targets.
- Where the PEL includes a “skin” notation, dermal absorption can contribute to the dose — glove selection and hygiene facilities are part of compliance.
Frequently Asked Questions
What is the OSHA PEL for Titanium Dioxide?
The OSHA Permissible Exposure Limit (8-hour TWA) for Titanium Dioxide is 15 mg/m3.
What is the CAS number for Titanium Dioxide?
The CAS Registry Number for Titanium Dioxide is 13463-67-7.
What are the target organs for Titanium Dioxide?
The primary target organs are the Lungs.
How do you measure Titanium Dioxide in workplace air?
Use NIOSH analytical method NIOSH 0600 for air sampling and laboratory analysis.
What hazard class is Titanium Dioxide?
It is classified here as a Particulate / Dust (Particulate).