Carbon Monoxide (630-08-0)
Carbon Monoxide is a asphyxiant with CAS Registry Number 630-08-0. Under the OSHA air contaminants standard (29 CFR 1910.1000), its Permissible Exposure Limit (PEL) — the legal 8-hour time-weighted average (TWA) for general industry — is 50 ppm. The principal target organs are the Blood; cardiovascular, and workplace air is sampled and analyzed by NIOSH 6604.
Exposure Limits at a Glance
| Limit | Value | Basis |
|---|---|---|
| OSHA PEL (8-hr TWA) | 50 ppm | 29 CFR 1910.1000 |
| NIOSH REL | See note below | NIOSH Pocket Guide |
| Hazard Class | Asphyxiant | Asphyxiant |
| Target Organs | Blood; cardiovascular | NIOSH / OSHA |
| Sampling Method | NIOSH 6604 | NIOSH Manual of Analytical Methods |
NIOSH REL note: NIOSH RELs include short-term (ceiling) limits where acute toxicity dominates. The REL is a non-regulatory recommendation; where a NIOSH REL exists it is typically more protective than the OSHA PEL.
How It Enters the Body & Health Effects
Exposure to Carbon Monoxide is assessed against the Blood; cardiovascular — the organ systems most consistently affected in occupational studies. Employers must ensure no employee’s 8-hour TWA exceeds the 50 ppm PEL, and must use engineering controls, work practices, and — where required — respiratory protection to keep exposures at or below that level.
- Hazard class: Asphyxiant. Asphyxiant-class agents are managed with the hierarchy of controls (elimination, substitution, engineering controls, administrative controls, then PPE).
- Monitoring: collect personal air samples in the breathing zone and submit them under NIOSH 6604 for laboratory analysis.
- Medical surveillance: consult the OSHA substance-specific standards and the NIOSH Pocket Guide when the target organs are the Blood; cardiovascular.
Sampling & Compliance Notes
- Determine whether the exposure is a full-period 8-hour TWA or a short-term / ceiling scenario. Ceiling and STEL excursions apply to several Asphyxiant-class agents regardless of the 8-hour average.
- Calibrate personal sampling pumps before and after each shift and record flow rates; method NIOSH 6604 specifies media, flow, and analysis.
- Compare analytical results to the OSHA PEL of 50 ppm and the NIOSH REL. Document the higher of the two for internal exposure-control targets.
- Where the PEL includes a “skin” notation, dermal absorption can contribute to the dose — glove selection and hygiene facilities are part of compliance.
Frequently Asked Questions
What is the OSHA PEL for Carbon Monoxide?
The OSHA Permissible Exposure Limit (8-hour TWA) for Carbon Monoxide is 50 ppm.
What is the CAS number for Carbon Monoxide?
The CAS Registry Number for Carbon Monoxide is 630-08-0.
What are the target organs for Carbon Monoxide?
The primary target organs are the Blood; cardiovascular.
How do you measure Carbon Monoxide in workplace air?
Use NIOSH analytical method NIOSH 6604 for air sampling and laboratory analysis.
What hazard class is Carbon Monoxide?
It is classified here as a Asphyxiant (Asphyxiant).